We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a healthier place. This was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, draw and keep the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and demonstrates our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and embodies the value we work to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We embody our purpose by sourcing the best science in the world, partnering with others in the healthcare system to increase access to our medicines, utilizing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.